The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management

Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 diabetes (T2DM). A vital aspect regarding HSP70 physiology is its versatility to induce antagonistic actions, depending...

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Detalles Bibliográficos
Autores principales: Krause, Mauricio, Heck, Thiago Gomes, Bittencourt, Aline, Scomazzon, Sofia Pizzato, Newsholme, Philip, Curi, Rui, Homem de Bittencourt, Paulo Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357135/
https://www.ncbi.nlm.nih.gov/pubmed/25814786
http://dx.doi.org/10.1155/2015/249205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357135/
https://www.ncbi.nlm.nih.gov/pubmed/25814786
http://dx.doi.org/10.1155/2015/249205

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