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PGE(2)-Induced IDO1 Inhibits the Capacity of Fully Mature DCs to Elicit an In Vitro Antileukemic Immune Response

In the last years, dendritic cells (DC) have been evaluated for antitumor vaccination. Although DC-based vaccines have raised great expectations, their clinical translation has been largely disappointing. For these results, several explanations have been proposed. In particular, the concomitant expr...

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Detalles Bibliográficos
Autores principales: Trabanelli, Sara, Lecciso, Mariangela, Salvestrini, Valentina, Cavo, Michele, Očadlíková, Darina, Lemoli, Roberto M., Curti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357138/
https://www.ncbi.nlm.nih.gov/pubmed/25815345
http://dx.doi.org/10.1155/2015/253191