Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life

BACKGROUND: We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if adjuvants were included in oral vaccine, piglets responded with antibody-mediated immunity (Vet Immunol Immunopathol 161(3–4):211–21, 2014). Here, we...

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Detalles Bibliográficos
Autores principales: Pasternak, J Alex, Ng, Siew Hon, Buchanan, Rachelle M, Mertins, Sonja, Mutwiri, George K, Gerdts, Volker, Wilson, Heather L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357157/
https://www.ncbi.nlm.nih.gov/pubmed/25889479
http://dx.doi.org/10.1186/s12917-015-0350-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357157/
https://www.ncbi.nlm.nih.gov/pubmed/25889479
http://dx.doi.org/10.1186/s12917-015-0350-8

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