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Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events

BACKGROUND: Hepatocellular carcinoma (HCC) is on the rise and the sixth most common cancer worldwide. To combat HCC effectively research is directed towards its early detection and the development of targeted therapies. Given the fact that epidermal growth factor (EGF) is an important mitogen for he...

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Detalles Bibliográficos
Autores principales: Borlak, Jürgen, Singh, Prashant, Gazzana, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357185/
https://www.ncbi.nlm.nih.gov/pubmed/25872475
http://dx.doi.org/10.1186/s12864-015-1312-z