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The acute effect of beta-guanidinopropionic acid versus creatine or placebo in healthy men (ABC Trial): study protocol for a randomized controlled trial

BACKGROUND: Despite adequate treatment, up to 30% of treated antihypertensive patients with primary, uncomplicated hypertension remain uncontrolled. We proposed that high intracellular activity of the ATP regenerating enzyme creatine kinase (CK) increases pressor responses and hypertension risk. In...

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Detalles Bibliográficos
Autores principales: Karamat, Fares A, Horjus, Deborah L, Haan, Yentl C, van der Woude, Lisa, Oudman, Inge, van Montfrans, Gert A, Clark, Joseph F, Brewster, Lizzy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357188/
https://www.ncbi.nlm.nih.gov/pubmed/25888414
http://dx.doi.org/10.1186/s13063-015-0581-9