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Effect of plasmid replication deregulation via inc mutations on E. coli proteome & simple flux model analysis
When the replication of a plasmid based on sucrose selection is deregulated via the inc1 and inc2 mutations, high copy numbers (7,000 or greater) are attained while the growth rate on minimal medium is negligibly affected. Adaptions were assumed to be required in order to sustain the growth rate. Pr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357208/ https://www.ncbi.nlm.nih.gov/pubmed/25890349 http://dx.doi.org/10.1186/s12934-015-0212-x |