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Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B

Due to its long half-life (78 h) and decay properties (77% electron capture, 23% β(+), E (max) = 897 keV, E (av) = 397 keV, Eγ = 909 keV, Iγ = 100%) (89)Zr is an appealing radionuclide for immunoPET imaging with whole IgG antibodies. Derivatives of the siderophore desferrioxamine-B (H(3)DFO) are the...

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Detalles Bibliográficos
Autores principales: Ma, Michelle T., Meszaros, Levente K., Paterson, Brett M., Berry, David J., Cooper, Maggie S., Ma, Yongmin, Hider, Robert C., Blower, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357251/
https://www.ncbi.nlm.nih.gov/pubmed/25351250
http://dx.doi.org/10.1039/c4dt02978j