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A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration

Both lung disease and elevation of blood glucose are associated with increased glucose concentration (from 0.4 to ~4.0 mM) in the airway surface liquid (ASL). This perturbation of ASL glucose makes the airway more susceptible to infection by respiratory pathogens. ASL is minute (~1 μl/cm(2)) and the...

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Detalles Bibliográficos
Autores principales: Helassa, Nordine, Garnett, James P., Farrant, Matthew, Khan, Faaizah, Pickup, John C., Hahn, Klaus M., MacNevin, Christopher J., Tarran, Robert, Baines, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357280/
https://www.ncbi.nlm.nih.gov/pubmed/25220254
http://dx.doi.org/10.1042/BJ20141041