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Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear

The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic chick. The chicken homolog of Numb is expresse...

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Detalles Bibliográficos
Autores principales: Eddison, Mark, Weber, Sara J., Ariza-McNaughton, Linda, Lewis, Julian, Daudet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357303/
https://www.ncbi.nlm.nih.gov/pubmed/25814931
http://dx.doi.org/10.3389/fncel.2015.00074