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Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known. To investigate Th2 cell responses to pulmonary fungal infection, we developed a peptide-MHCII tetramer to track antigen-specific C...

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Detalles Bibliográficos
Autores principales: Wiesner, Darin L., Specht, Charles A., Lee, Chrono K., Smith, Kyle D., Mukaremera, Liliane, Lee, S. Thera, Lee, Chun G., Elias, Jack A., Nielsen, Judith N., Boulware, David R., Bohjanen, Paul R., Jenkins, Marc K., Levitz, Stuart M., Nielsen, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357429/
https://www.ncbi.nlm.nih.gov/pubmed/25764512
http://dx.doi.org/10.1371/journal.ppat.1004701