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Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known. To investigate Th2 cell responses to pulmonary fungal infection, we developed a peptide-MHCII tetramer to track antigen-specific C...
Autores principales: | Wiesner, Darin L., Specht, Charles A., Lee, Chrono K., Smith, Kyle D., Mukaremera, Liliane, Lee, S. Thera, Lee, Chun G., Elias, Jack A., Nielsen, Judith N., Boulware, David R., Bohjanen, Paul R., Jenkins, Marc K., Levitz, Stuart M., Nielsen, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357429/ https://www.ncbi.nlm.nih.gov/pubmed/25764512 http://dx.doi.org/10.1371/journal.ppat.1004701 |
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