GSK3β Inhibition Promotes Synaptogenesis in Drosophila and Mammalian Neurons

The PI3K-dependent activation of AKT results in the inhibition of GSK3β in most signaling pathways. These kinases regulate multiple neuronal processes including the control of synapse number as shown for Drosophila and rodents. Alzheimer disease’s patients exhibit high levels of circulating GSK3β an...

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Detalles Bibliográficos
Autores principales: Cuesto, Germán, Jordán-Álvarez, Sheila, Enriquez-Barreto, Lilian, Ferrús, Alberto, Morales, Miguel, Acebes, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357437/
https://www.ncbi.nlm.nih.gov/pubmed/25764078
http://dx.doi.org/10.1371/journal.pone.0118475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357437/
https://www.ncbi.nlm.nih.gov/pubmed/25764078
http://dx.doi.org/10.1371/journal.pone.0118475

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