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GSK3β Inhibition Promotes Synaptogenesis in Drosophila and Mammalian Neurons
The PI3K-dependent activation of AKT results in the inhibition of GSK3β in most signaling pathways. These kinases regulate multiple neuronal processes including the control of synapse number as shown for Drosophila and rodents. Alzheimer disease’s patients exhibit high levels of circulating GSK3β an...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357437/ https://www.ncbi.nlm.nih.gov/pubmed/25764078 http://dx.doi.org/10.1371/journal.pone.0118475 |