On the Role of Protein Disulfide Isomerase in the Retrograde Cell Transport of Secreted Phospholipases A(2)

Following the finding that ammodytoxin (Atx), a neurotoxic secreted phospholipase A(2) (sPLA(2)) in snake venom, binds specifically to protein disulfide isomerase (PDI) in vitro we show that these proteins also interact in living rat PC12 cells that are able to internalize this group IIA (GIIA) sPLA...

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Detalles Bibliográficos
Autores principales: Oberčkal, Jernej, Kovačič, Lidija, Šribar, Jernej, Leonardi, Adrijana, Dolinar, Klemen, Pucer Janež, Anja, Križaj, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357439/
https://www.ncbi.nlm.nih.gov/pubmed/25763817
http://dx.doi.org/10.1371/journal.pone.0120692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357439/
https://www.ncbi.nlm.nih.gov/pubmed/25763817
http://dx.doi.org/10.1371/journal.pone.0120692

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