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V-Myc Immortalizes Human Neural Stem Cells in the Absence of Pluripotency-Associated Traits

A better understanding of the molecular mechanisms governing stem cell self-renewal will foster the use of different types of stem cells in disease modeling and cell therapy strategies. Immortalization, understood as the capacity for indefinite expansion, is needed for the generation of any cell lin...

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Detalles Bibliográficos
Autores principales: Pino-Barrio, María José, García-García, Elisa, Menéndez, Pablo, Martínez-Serrano, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357445/
https://www.ncbi.nlm.nih.gov/pubmed/25764185
http://dx.doi.org/10.1371/journal.pone.0118499