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V-Myc Immortalizes Human Neural Stem Cells in the Absence of Pluripotency-Associated Traits
A better understanding of the molecular mechanisms governing stem cell self-renewal will foster the use of different types of stem cells in disease modeling and cell therapy strategies. Immortalization, understood as the capacity for indefinite expansion, is needed for the generation of any cell lin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357445/ https://www.ncbi.nlm.nih.gov/pubmed/25764185 http://dx.doi.org/10.1371/journal.pone.0118499 |