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Ploidy variation in multinucleate cells changes under stress

Ploidy variation is found in contexts as diverse as solid tumors, drug resistance in fungal infection, and normal development. Altering chromosome or genome copy number supports adaptation to fluctuating environments but is also associated with fitness defects attributed to protein imbalances. Both...

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Detalles Bibliográficos
Autores principales: Anderson, Cori A., Roberts, Samantha, Zhang, Huaiying, Kelly, Courtney M., Kendall, Alexxy, Lee, ChangHwan, Gerstenberger, John, Koenig, Aaron B., Kabeche, Ruth, Gladfelter, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357512/
https://www.ncbi.nlm.nih.gov/pubmed/25631818
http://dx.doi.org/10.1091/mbc.E14-09-1375