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Convergent Regulation of Neuronal Differentiation and Erk and Akt Kinases in Human Neural Progenitor Cells by Lysophosphatidic Acid, Sphingosine 1-Phosphate, and LIF: Specific Roles for the LPA1 Receptor

The bioactive lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have diverse effects on the developing nervous system and neural progenitors, but the molecular basis for their pleiotropic effects is poorly understood. We previously defined LPA and S1P signaling in proli...

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Detalles Bibliográficos
Autores principales: Callihan, Phillip, Ali, Mourad W., Salazar, Hector, Quach, Nhat, Wu, Xian, Stice, Steven L., Hooks, Shelley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357610/
https://www.ncbi.nlm.nih.gov/pubmed/25424429
http://dx.doi.org/10.1177/1759091414558416