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Computational and molecular tools for scalable rAAV-mediated genome editing

The rapid discovery of potential driver mutations through large-scale mutational analyses of human cancers generates a need to characterize their cellular phenotypes. Among the techniques for genome editing, recombinant adeno-associated virus (rAAV)-mediated gene targeting is suited for knock-in of...

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Detalles Bibliográficos
Autores principales: Stoimenov, Ivaylo, Ali, Muhammad Akhtar, Pandzic, Tatjana, Sjöblom, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357690/
https://www.ncbi.nlm.nih.gov/pubmed/25488813
http://dx.doi.org/10.1093/nar/gku1286