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SwiftLib: rapid degenerate-codon-library optimization through dynamic programming
Degenerate codon (DC) libraries efficiently address the experimental library-size limitations of directed evolution by focusing diversity toward the positions and toward the amino acids (AAs) that are most likely to generate hits; however, manually constructing DC libraries is challenging, error pro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357694/ https://www.ncbi.nlm.nih.gov/pubmed/25539925 http://dx.doi.org/10.1093/nar/gku1323 |