Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits

The human genome contains about 1.5 million Alu elements, which are transcribed into Alu RNAs by RNA polymerase III. Their expression is upregulated following stress and viral infection, and they associate with the SRP9/14 protein dimer in the cytoplasm forming Alu RNPs. Using cell-free translation,...

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Detalles Bibliográficos
Autores principales: Ivanova, Elena, Berger, Audrey, Scherrer, Anne, Alkalaeva, Elena, Strub, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357698/
https://www.ncbi.nlm.nih.gov/pubmed/25697503
http://dx.doi.org/10.1093/nar/gkv048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357698/
https://www.ncbi.nlm.nih.gov/pubmed/25697503
http://dx.doi.org/10.1093/nar/gkv048

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