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Human Rap1 modulates TRF2 attraction to telomeric DNA

More than two decades of genetic research have identified and assigned main biological functions of shelterin proteins that safeguard telomeres. However, a molecular mechanism of how each protein subunit contributes to the protecting function of the whole shelterin complex remains elusive. Human Rep...

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Detalles Bibliográficos
Autores principales: Janoušková, Eliška, Nečasová, Ivona, Pavloušková, Jana, Zimmermann, Michal, Hluchý, Milan, Marini, Victoria, Nováková, Monika, Hofr, Ctirad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357705/
https://www.ncbi.nlm.nih.gov/pubmed/25675958
http://dx.doi.org/10.1093/nar/gkv097