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Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum

To achieve drug resistance Leishmania parasite alters gene copy number by using its repeated sequences widely distributed through the genome. Even though homologous recombination (HR) is ascribed to maintain genome stability, this eukaryote exploits this potent mechanism driven by the Rad51 recombin...

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Detalles Bibliográficos
Autores principales: Genois, Marie-Michelle, Plourde, Marie, Éthier, Chantal, Roy, Gaétan, Poirier, Guy G., Ouellette, Marc, Masson, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357719/
https://www.ncbi.nlm.nih.gov/pubmed/25712090
http://dx.doi.org/10.1093/nar/gkv118