Unraveling the mechanistic features of RNA polymerase II termination by the 5′-3′ exoribonuclease Rat1

Within a complex with Rai1, the 5′-3′ exoribonuclease Rat1 promotes termination of RNA polymerase II (RNAPII) on protein-coding genes, but its underlying molecular mechanism is still poorly understood. Using in vitro transcription termination assays, we have found that RNAPII is prone to more effect...

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Detalles Bibliográficos
Autores principales: Park, Jieun, Kang, Myungjin, Kim, Minkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357727/
https://www.ncbi.nlm.nih.gov/pubmed/25722373
http://dx.doi.org/10.1093/nar/gkv133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357727/
https://www.ncbi.nlm.nih.gov/pubmed/25722373
http://dx.doi.org/10.1093/nar/gkv133

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