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Unraveling the mechanistic features of RNA polymerase II termination by the 5′-3′ exoribonuclease Rat1
Within a complex with Rai1, the 5′-3′ exoribonuclease Rat1 promotes termination of RNA polymerase II (RNAPII) on protein-coding genes, but its underlying molecular mechanism is still poorly understood. Using in vitro transcription termination assays, we have found that RNAPII is prone to more effect...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357727/ https://www.ncbi.nlm.nih.gov/pubmed/25722373 http://dx.doi.org/10.1093/nar/gkv133 |