Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging

The ability of DNA glycosylases to rapidly and efficiently detect lesions among a vast excess of nondamaged DNA bases is vitally important in base excision repair (BER). Here, we use single molecule imaging by atomic force microscopy (AFM) supported by a 2-aminopurine fluorescence base flipping assa...

Descripción completa

Detalles Bibliográficos
Autores principales: Buechner, Claudia N., Maiti, Atanu, Drohat, Alexander C., Tessmer, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357730/
https://www.ncbi.nlm.nih.gov/pubmed/25712093
http://dx.doi.org/10.1093/nar/gkv139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357730/
https://www.ncbi.nlm.nih.gov/pubmed/25712093
http://dx.doi.org/10.1093/nar/gkv139

Ejemplares similares