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Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging

The ability of DNA glycosylases to rapidly and efficiently detect lesions among a vast excess of nondamaged DNA bases is vitally important in base excision repair (BER). Here, we use single molecule imaging by atomic force microscopy (AFM) supported by a 2-aminopurine fluorescence base flipping assa...

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Detalles Bibliográficos
Autores principales:	Buechner, Claudia N., Maiti, Atanu, Drohat, Alexander C., Tessmer, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357730/ https://www.ncbi.nlm.nih.gov/pubmed/25712093 http://dx.doi.org/10.1093/nar/gkv139

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