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Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome

The Escherichia coli SeqA protein binds to newly replicated, hemimethylated DNA behind replication forks and forms structures consisting of several hundred SeqA molecules bound to about 100 kb of DNA. It has been suggested that SeqA structures either direct the new sister DNA molecules away from eac...

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Detalles Bibliográficos
Autores principales: Helgesen, Emily, Fossum-Raunehaug, Solveig, Sætre, Frank, Schink, Kay Oliver, Skarstad, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357733/
https://www.ncbi.nlm.nih.gov/pubmed/25722374
http://dx.doi.org/10.1093/nar/gkv146