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Leveraging Metabolomics to Assess the Next Generation of Temozolomide-based Therapeutic Approaches for Glioblastomas

Glioblastoma multiforme (GBM) is the most common adult primary tumor of the central nervous system. The current standard of care for glioblastoma patients involves a combination of surgery, radiotherapy and chemotherapy with the alkylating agent temozolomide. Several mechanisms underlying the inhere...

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Detalles Bibliográficos
Autores principales: St-Coeur, Patrick-Denis, Touaibia, Mohamed, Cuperlovic-Culf, Miroslava, Morin, Pier Jr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357826/
https://www.ncbi.nlm.nih.gov/pubmed/23732626
http://dx.doi.org/10.1016/j.gpb.2013.04.003