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Integration-free Methods for Generating Induced Pluripotent Stem Cells

Induced pluripotent stem (iPS) cells can be generated from mouse or human fibroblasts by exogenous expression of four factors, Oct4, Sox2, Klf4 and c-Myc, and hold great potential for transplantation therapies and regenerative medicine. However, use of retroviral vectors during iPS cell generation h...

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Detalles Bibliográficos
Autores principales: Zhou, Yi-ye, Zeng, Fanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357834/
https://www.ncbi.nlm.nih.gov/pubmed/24121200
http://dx.doi.org/10.1016/j.gpb.2013.09.008