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Integration-free Methods for Generating Induced Pluripotent Stem Cells
Induced pluripotent stem (iPS) cells can be generated from mouse or human fibroblasts by exogenous expression of four factors, Oct4, Sox2, Klf4 and c-Myc, and hold great potential for transplantation therapies and regenerative medicine. However, use of retroviral vectors during iPS cell generation h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357834/ https://www.ncbi.nlm.nih.gov/pubmed/24121200 http://dx.doi.org/10.1016/j.gpb.2013.09.008 |