Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η

A single injection of N-methyl-D-aspartate receptor (NMDAR) antagonists produces a rapid antidepressant response. Lasting changes in the synapse structure and composition underlie the effectiveness of these drugs. We recently discovered that rapid antidepressants cause a shift in the γ-aminobutyric...

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Detalles Bibliográficos
Autores principales: Workman, E R, Haddick, P C G, Bush, K, Dilly, G A, Niere, F, Zemelman, B V, Raab-Graham, K F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357863/
https://www.ncbi.nlm.nih.gov/pubmed/25560757
http://dx.doi.org/10.1038/mp.2014.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357863/
https://www.ncbi.nlm.nih.gov/pubmed/25560757
http://dx.doi.org/10.1038/mp.2014.165

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