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Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η

A single injection of N-methyl-D-aspartate receptor (NMDAR) antagonists produces a rapid antidepressant response. Lasting changes in the synapse structure and composition underlie the effectiveness of these drugs. We recently discovered that rapid antidepressants cause a shift in the γ-aminobutyric...

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Detalles Bibliográficos
Autores principales:	Workman, E R, Haddick, P C G, Bush, K, Dilly, G A, Niere, F, Zemelman, B V, Raab-Graham, K F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Immediate Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357863/ https://www.ncbi.nlm.nih.gov/pubmed/25560757 http://dx.doi.org/10.1038/mp.2014.165

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