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Blood cell transcriptomic-based early biomarkers of adverse programming effects of gestational calorie restriction and their reversibility by leptin supplementation

The challenge of preventing major chronic diseases requires reliable, early biomarkers. Gestational mild undernutrition in rats is enough to program the offspring to develop later pathologies; the intake of leptin, a breastmilk component, during lactation may reverse these programming effects. We us...

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Detalles Bibliográficos
Autores principales: Konieczna, Jadwiga, Sánchez, Juana, Palou, Mariona, Picó, Catalina, Palou, Andreu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357898/
https://www.ncbi.nlm.nih.gov/pubmed/25766068
http://dx.doi.org/10.1038/srep09088