Cargando…
Blood cell transcriptomic-based early biomarkers of adverse programming effects of gestational calorie restriction and their reversibility by leptin supplementation
The challenge of preventing major chronic diseases requires reliable, early biomarkers. Gestational mild undernutrition in rats is enough to program the offspring to develop later pathologies; the intake of leptin, a breastmilk component, during lactation may reverse these programming effects. We us...
Autores principales: | Konieczna, Jadwiga, Sánchez, Juana, Palou, Mariona, Picó, Catalina, Palou, Andreu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357898/ https://www.ncbi.nlm.nih.gov/pubmed/25766068 http://dx.doi.org/10.1038/srep09088 |
Ejemplares similares
-
Oral Leptin Treatment in Suckling Rats Ameliorates Detrimental Effects in Hypothalamic Structure and Function Caused by Maternal Caloric Restriction during Gestation
por: Konieczna, Jadwiga, et al.
Publicado: (2013) -
Leptin Intake at Physiological Doses Throughout Lactation in Male Wistar Rats Normalizes the Decreased Density of Tyrosine Hydroxylase-Immunoreactive Fibers in the Stomach Caused by Mild Gestational Calorie Restriction
por: Szostaczuk, Nara, et al.
Publicado: (2018) -
Myo-Inositol Supplementation in Suckling Rats Protects against Adverse Programming Outcomes on Hypothalamic Structure Caused by Mild Gestational Calorie Restriction, Partially Comparable to Leptin Effects
por: Castillo, Pedro, et al.
Publicado: (2021) -
Sexual dimorphism in the lasting effects of moderate caloric restriction during gestation on energy homeostasis in rats is related with fetal programming of insulin and leptin resistance
por: Palou, Mariona, et al.
Publicado: (2010) -
Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction
por: Picó, Catalina, et al.
Publicado: (2012)