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Transmitted/Founder Hepatitis C Viruses Induce Cell-Type- and Genotype-Specific Differences in Innate Signaling within the Liver

Hepatitis C virus (HCV) infection leads to persistence in the majority of cases despite triggering complex innate immune responses within the liver. Although hepatocytes are the preferred site for HCV replication, nonparenchymal cells (NPCs) can also contribute to antiviral immunity. Recent innovati...

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Detalles Bibliográficos
Autores principales: Mitchell, Angela M., Stone, Amy E. L., Cheng, Linling, Ballinger, Kimberly, Edwards, Michael G., Stoddard, Mark, Li, Hui, Golden-Mason, Lucy, Shaw, George M., Khetani, Salman, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357998/
https://www.ncbi.nlm.nih.gov/pubmed/25714713
http://dx.doi.org/10.1128/mBio.02510-14