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Glycan Engagement Dictates Hydrocephalus Induction by Serotype 1 Reovirus

Receptors expressed on the host cell surface adhere viruses to target cells and serve as determinants of viral tropism. Several viruses bind cell surface glycans to facilitate entry, but the contribution of specific glycan moieties to viral disease is incompletely understood. Reovirus provides a tra...

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Detalles Bibliográficos
Autores principales: Stencel-Baerenwald, Jennifer, Reiss, Kerstin, Blaum, Bärbel S., Colvin, Daniel, Li, Xiao-Nan, Abel, Ty, Boyd, Kelli, Stehle, Thilo, Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358001/
https://www.ncbi.nlm.nih.gov/pubmed/25736887
http://dx.doi.org/10.1128/mBio.02356-14