RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA

Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discriminates bet...

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Detalles Bibliográficos
Autores principales: Anchisi, Stéphanie, Guerra, Jessica, Garcin, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358010/
https://www.ncbi.nlm.nih.gov/pubmed/25736886
http://dx.doi.org/10.1128/mBio.02349-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358010/
https://www.ncbi.nlm.nih.gov/pubmed/25736886
http://dx.doi.org/10.1128/mBio.02349-14

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