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RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA

Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discriminates bet...

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Detalles Bibliográficos
Autores principales:	Anchisi, Stéphanie, Guerra, Jessica, Garcin, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358010/ https://www.ncbi.nlm.nih.gov/pubmed/25736886 http://dx.doi.org/10.1128/mBio.02349-14

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