Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study

Ursodeoxycholic acid and its main conjugate glycoursodeoxycholic acid are bile acids with neuroprotective properties. Our previous studies demonstrated their anti-apoptotic, anti-inflammatory, and antioxidant properties in neural cells exposed to elevated levels of unconjugated bilirubin (UCB) as in...

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Detalles Bibliográficos
Autores principales: Palmela, Inês, Correia, Leonor, Silva, Rui F. M., Sasaki, Hiroyuki, Kim, Kwang S., Brites, Dora, Brito, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358072/
https://www.ncbi.nlm.nih.gov/pubmed/25821432
http://dx.doi.org/10.3389/fnins.2015.00080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358072/
https://www.ncbi.nlm.nih.gov/pubmed/25821432
http://dx.doi.org/10.3389/fnins.2015.00080

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