Akt-mediated phosphorylation of Oct4 is associated with the proliferation of stem-like cancer cells

Oct4 protein encoded by POU5F1 plays a pivotal role in maintaining the self-renewal of pluripotent stem cells; however, its presence in cancer cells remains controversial. In the present study, we provided evidence that the transcripts of authentic OCT4 gene (OCT4A) and its multiple pseudogenes were...

Descripción completa

Detalles Bibliográficos
Autores principales: ZHAO, QING-WEI, ZHOU, YAN-WEN, LI, WEN-XIN, KANG, BO, ZHANG, XIAO-QIAN, YANG, YING, CHENG, JIE, YIN, SHENG-YONG, TONG, YING, HE, JIAN-QIN, YAO, HANG-PING, ZHENG, MIN, WANG, YING-JIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358081/
https://www.ncbi.nlm.nih.gov/pubmed/25625591
http://dx.doi.org/10.3892/or.2015.3752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358081/
https://www.ncbi.nlm.nih.gov/pubmed/25625591
http://dx.doi.org/10.3892/or.2015.3752

Ejemplares similares