Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes

The phosphoinositide 3-kinase (PI 3-kinase, PI3K) pathway transduces signals critical for lymphocyte function. PI3K generates the phospholipid PIP(3) at the plasma membrane to recruit proteins that contain pleckstrin homology (PH) domains – a conserved domain found in hundreds of mammalian proteins....

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Detalles Bibliográficos
Autores principales: Wang, Xinxin, Hills, Leonard Benjamin, Huang, Yina Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358224/
https://www.ncbi.nlm.nih.gov/pubmed/25821452
http://dx.doi.org/10.3389/fimmu.2015.00117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358224/
https://www.ncbi.nlm.nih.gov/pubmed/25821452
http://dx.doi.org/10.3389/fimmu.2015.00117

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