Cargando…
Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes
The phosphoinositide 3-kinase (PI 3-kinase, PI3K) pathway transduces signals critical for lymphocyte function. PI3K generates the phospholipid PIP(3) at the plasma membrane to recruit proteins that contain pleckstrin homology (PH) domains – a conserved domain found in hundreds of mammalian proteins....
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358224/ https://www.ncbi.nlm.nih.gov/pubmed/25821452 http://dx.doi.org/10.3389/fimmu.2015.00117 |