Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus

Calcineurin is a key protein phosphatase required for hyphal growth and virulence in Aspergillus fumigatus, making it an attractive antifungal target. However, currently available calcineurin inhibitors, FK506 and cyclosporine A, are immunosuppressive, limiting usage in the treatment of patients wit...

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Detalles Bibliográficos
Autores principales: Juvvadi, Praveen R., Ma, Yan, Richards, Amber D., Soderblom, Erik J., Moseley, M. Arthur, Lamoth, Frédéric, Steinbach, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358225/
https://www.ncbi.nlm.nih.gov/pubmed/25821446
http://dx.doi.org/10.3389/fmicb.2015.00175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358225/
https://www.ncbi.nlm.nih.gov/pubmed/25821446
http://dx.doi.org/10.3389/fmicb.2015.00175

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