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Intravital and Whole-Organ Imaging Reveals Capture of Melanoma-Derived Antigen by Lymph Node Subcapsular Macrophages Leading to Widespread Deposition on Follicular Dendritic Cells

Aberrant antigens expressed by tumor cells, such as in melanoma, are often associated with humoral immune responses, which may in turn influence tumor progression. Despite recent data showing the central role of adaptive immune responses on cancer spread or control, it remains poorly understood wher...

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Detalles Bibliográficos
Autores principales: Moalli, Federica, Proulx, Steven T., Schwendener, Reto, Detmar, Michael, Schlapbach, Christoph, Stein, Jens V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358226/
https://www.ncbi.nlm.nih.gov/pubmed/25821451
http://dx.doi.org/10.3389/fimmu.2015.00114