RNA Toxicity and Missplicing in the Common Eye Disease Fuchs Endothelial Corneal Dystrophy

Fuchs endothelial corneal dystrophy (FECD) is an inherited degenerative disease that affects the internal endothelial cell monolayer of the cornea and can result in corneal edema and vision loss in severe cases. FECD affects ∼5% of middle-aged Caucasians in the United States and accounts for >14,...

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Detalles Bibliográficos
Autores principales: Du, Jintang, Aleff, Ross A., Soragni, Elisabetta, Kalari, Krishna, Nie, Jinfu, Tang, Xiaojia, Davila, Jaime, Kocher, Jean-Pierre, Patel, Sanjay V., Gottesfeld, Joel M., Baratz, Keith H., Wieben, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358235/
https://www.ncbi.nlm.nih.gov/pubmed/25593321
http://dx.doi.org/10.1074/jbc.M114.621607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358235/
https://www.ncbi.nlm.nih.gov/pubmed/25593321
http://dx.doi.org/10.1074/jbc.M114.621607

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