Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

Kinesins are a superfamily of microtubule-based ATP-powered motors, important for multiple, essential cellular functions. How microtubule binding stimulates their ATPase and controls force generation is not understood. To address this fundamental question, we visualized microtubule-bound kinesin-1 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Atherton, Joseph, Farabella, Irene, Yu, I-Mei, Rosenfeld, Steven S, Houdusse, Anne, Topf, Maya, Moores, Carolyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358365/
https://www.ncbi.nlm.nih.gov/pubmed/25209998
http://dx.doi.org/10.7554/eLife.03680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358365/
https://www.ncbi.nlm.nih.gov/pubmed/25209998
http://dx.doi.org/10.7554/eLife.03680

Ejemplares similares