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Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Kinesins are a superfamily of microtubule-based ATP-powered motors, important for multiple, essential cellular functions. How microtubule binding stimulates their ATPase and controls force generation is not understood. To address this fundamental question, we visualized microtubule-bound kinesin-1 a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358365/ https://www.ncbi.nlm.nih.gov/pubmed/25209998 http://dx.doi.org/10.7554/eLife.03680 |