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Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation

S-phase cyclin-dependent kinases (CDKs) stimulate replication initiation and accelerate progression through the replication timing program, but it is unknown which CDK substrates are responsible for these effects. CDK phosphorylation of the replication factor TICRR (TopBP1-interacting checkpoint and...

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Detalles Bibliográficos
Autores principales: Sansam, Courtney G., Goins, Duane, Siefert, Joseph C., Clowdus, Emily A., Sansam, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358407/
https://www.ncbi.nlm.nih.gov/pubmed/25737283
http://dx.doi.org/10.1101/gad.246827.114