The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

The human PYHIN proteins, AIM2, IFI16, IFIX, and MNDA, are critical regulators of immune response, transcription, apoptosis, and cell cycle. However, their protein interactions and underlying mechanisms remain largely uncharacterized. Here, we provide the interaction network for all PYHIN proteins a...

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Detalles Bibliográficos
Autores principales: Diner, Benjamin A, Li, Tuo, Greco, Todd M, Crow, Marni S, Fuesler, John A, Wang, Jennifer, Cristea, Ileana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358659/
https://www.ncbi.nlm.nih.gov/pubmed/25665578
http://dx.doi.org/10.15252/msb.20145808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358659/
https://www.ncbi.nlm.nih.gov/pubmed/25665578
http://dx.doi.org/10.15252/msb.20145808

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