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Single peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells

BACKGROUND: The purpose of this study was to construct hollow mesoporous silica nanoparticles (HMSN) decorated with tLyp-1 peptide (tHMSN) for dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells. METHODS: HMSN were synthesized de novo using a novel cationic surfactant-assis...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Chen, Qing, Xu, Ming, Guan, Guannan, Hu, Wen, Liang, Ying, Zhao, Xiuli, Qiao, Mingxi, Chen, Dawei, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358692/
https://www.ncbi.nlm.nih.gov/pubmed/25834425
http://dx.doi.org/10.2147/IJN.S75098